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Comparative analysis of Topical Glucosamine Sulfate and Proprioceptive Exercises on Pain and Functional Disability in Knee Osteoarthritis

Comparative analysis of Topical Glucosamine Sulfate and Proprioceptive Exercises on Pain and Functional Disability in Knee Osteoarthritis

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220115053712N1
Enrollment
38
Registered
2022-02-02
Start date
2021-11-15
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis with grade 1, 2 and 3. Osteoarthritis of knee

Interventions

Intervention 1: intervention group 2
group-B will be treated with proprioceptive exercises. The proprioceptive exercises are Standing on 1 leg [eyes open and closed], Knee flexion and extension exercises (sitting position with a chair an

Sponsors

Muhammad Institute of Medical and Allied Sciences, Multan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: bilateral knee OA with grade 1,2 and 3 Age 45-70 years Both genders (male and female) Cartilage degeneration Local biomechanical factors (e.g., obesity, joint deformity, muscle weakness) Nutritional factors Postmenopausal women

Exclusion criteria

Exclusion criteria: Rheumatoid arthritis Neurological disorders (e.g., Alzheimer’s disease, Parkinson’s disease) Knee replacement Steroidal injection in the past 2 months Neuropathy Tumor Knee fractures Knee OA with grade 4

Design outcomes

Secondary

MeasureTime frame
To reduce stiffness, muscle tone strength increases and joint receptor function raised. Timepoint: before and after treatment(6 weeks). Method of measurement: Numerical Pain Rating Scale (NPRS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC).

Primary

MeasureTime frame
Pain and functional disability. Timepoint: before and after treatment (6 weeks). Method of measurement: Numerical Pain Rating Scale (NPRS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC).

Countries

Pakistan

Contacts

Public ContactDr.Zahid Manzoor

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan

drhifzaarif@mimas.edu.pk+92 309 7697428

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026