The effect of St. Thomas cold and warm blood cardioplegia on coronary sinus and arterial blood gases, in patients undergoing coronary artery surgery.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220112053697N1

Enrollment

Registered

2022-05-11

Start date

2022-04-30

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing heart coronary artery bypass graft surgery. Intraoperative cardiac arrest during cardiac surgery

Interventions

Intervention 1: Patients in this group receive warm St. Thomas cardioplegia with a temperature of 37-36 ° C.Combination dose of St. Thomas 2 cardioplegia according to the formula20mmol / l potassium c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Ef above 30% No severe AI Lack of recent MI Patients who are not redo No pacemaker Patient consent to conduct research

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Determination of mean serum levels of pH of coronary sinus. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.;Determination of arterial blood gas parameters. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.;Determination of mean serum levels of lactate of coronary sinus. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.;Determination of mean serum levels of SVO2 of coronary sinus. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.	—

Measure

Time frame

Determination of mean serum levels of pH of coronary sinus. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.;Determination of arterial blood gas parameters. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.;Determination of mean serum levels of lactate of coronary sinus. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.;Determination of mean serum levels of SVO2 of coronary sinus. Timepoint: Measurement at two times, before the aortic clamp and also up to two minutes after the aortic clamp is opened. Method of measurement: Laboratory analysis of blood sample parameters.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiyousha Hemmati Tabari

Shahid Rajaei Cardiovascular Research and Training Center

N.hemmati@rhc.ac.ir+98 11 3247 8669

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026