The effect of application of dexamethasone in the middle ear during surgery

The effect of application of dexamethasone in the middle ear during stapedotomy on hearing results of patients with otosclerosis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220111053690N1

Enrollment

Registered

2022-05-01

Start date

2022-04-21

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

otosclerosis. Otosclerosis

Interventions

Intervention 1: Intervention group: In the control group, routine stapedotomy will be performed, and in the intervention group, immediately after perforation of the footplate by the perforator, 0.3 cc

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with otosclerosis whose conductive hearing impairment exceeds 30 dB on recent audiometry in the affected ear

Exclusion criteria

Exclusion criteria: Patients who have a history of previous stapedotomy surgery a history of other ear diseases, such as meningitis or upper semicircular canal dehiscence will be excluded if they do not return within the specified time after surgery.

Design outcomes

Primary

Measure	Time frame
Hearing improvement after dexamethasone use during middle ear surgery in otosclerosis in patients with a gap of 30 dB. Timepoint: Before and 6 months after complete high frequency audiometric stapedotomy at the audiometry center. Method of measurement: Audiometry and questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehrooz Amirzargar

Tehran University of Medical Sciences

amirzargarb@yahoo.com+98 21 6119 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026