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effect of aspirin on permanent Internal Jugular dialysis catheter patency

Evaluation of the effect of aspirin consumption on permanent Internal Jugular dialysis catheter patency in End Stage Renal Disease (ESRD) patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220110053680N1
Enrollment
84
Registered
2022-12-09
Start date
2022-07-23
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end stage renal disease (ESRD) , patency of internal jugular permcath , aspirin consumption. Encounter for adjustment and management of vascular access device

Interventions

Intervention 1: Intervention group: Receive 80 mg aspirin orally, once a day , for 6 months, made by Parsdarou Company The survi

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patient has ESRD and Glomerular Filtration Rate (GFR) <15ml / min / 1.73 m^2. At least one month should be passed since the start of hemodialysis maintenance. At least one month and at most one year should be passed since the installation of the internal jugular permcath . There shouldn't have any definitive contraindication for normal use of aspirin

Exclusion criteria

Exclusion criteria: Current aspirin use at the time of entrance in the study Presence of a known underlying disease that increases the risk of thrombosis (lupus, antiphospholipid syndrome, presence of nephrotic syndromes) use of anticoagulants (warfarin, heparin, apixaban, rivaroxaban, plavix) use of Tarulac Catheter infection before beginning the study Incomplete patient document regarding the items required in the study Patient disfavor with inclusion in the study

Design outcomes

Primary

MeasureTime frame
Duration of internal jugular permcath patency. Timepoint: Weekly. Method of measurement: Number of days that permcath has function during the 6 month of the study.

Secondary

MeasureTime frame
Duration of time that patient has suffered from End Stage Renal Disease (ESRD). Timepoint: At onset of study. Method of measurement: Number of months passed since the diagnosis of ESRD and onset of hemodialysis.;History of heart failure. Timepoint: At onset of the study. Method of measurement: Ejection Fraction (EF) less than 50% according to echocardiography record in patient's file.;Hypertension. Timepoint: At onset of the study and in patients with hypertension, weekly until the end of the study. Method of measurement: Systolic blood pressure (SBP) = 140 mmHg or Diastolic blood pressure (DBP) = 90 mmHg according to patient's file.;Diabetes mellitus. Timepoint: At onset of the study. Method of measurement: Fast Blood Sugar (FBS) = 126 mg/dl according to patient's file.;Age. Timepoint: At onset of the study. Method of measurement: Asking from patient.;Sex. Timepoint: At onset of the study. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHanieh Davoodi

Zanjan University of Medical Sciences

md.101.2512@gmail.com+98 24 3344 3965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026