Investigating the effect of Spirulina platensis algae in the treatment of diabetes

Survey and Comparison of the effect of fortified yogurt enriched with fermented and non-fermented Spirulina Platensis extract on reducing oxidative stress in patients with type 2 diabetes mellitus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220108053663N1

Enrollment

100

Registered

2022-10-09

Start date

2022-09-21

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus. Diabetes mellitus due to underlying condition

Interventions

Intervention 1: Intervention group: After the patients visited the diabetes clinic for the plan, full explanations about the objectives of the study will be given to them during a one-hour training se

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Type 2 diabetes mellitus

Exclusion criteria

Exclusion criteria: Type1 diabetes mellitus Patients injecting insulin Age less than 40 and more than 70 years

Design outcomes

Primary

Measure	Time frame
Average changes in reduced glutathione levels in the blood serum of type 2 diabetics. Timepoint: Measurement of blood reduced glutathione levels before the intervention and 21 days after the intervention. Method of measurement: reduced glutathione blood level measurement kit.;Average changes in fasting blood sugar levels in the blood serum of type 2 diabetics. Timepoint: Measurement of fasting blood sugar before the intervention and 21 days after the intervention. Method of measurement: fasting blood sugar measurement kit.;Average changes in high reactive protein C level in blood serum of type 2 diabetic patients. Timepoint: Measurement of C protein with high reactivity in blood serum before the intervention and 21 days after the intervention. Method of measurement: C- Reactive protein measurement kit.	—

Measure

Time frame

Average changes in reduced glutathione levels in the blood serum of type 2 diabetics. Timepoint: Measurement of blood reduced glutathione levels before the intervention and 21 days after the intervention. Method of measurement: reduced glutathione blood level measurement kit.;Average changes in fasting blood sugar levels in the blood serum of type 2 diabetics. Timepoint: Measurement of fasting blood sugar before the intervention and 21 days after the intervention. Method of measurement: fasting blood sugar measurement kit.;Average changes in high reactive protein C level in blood serum of type 2 diabetic patients. Timepoint: Measurement of C protein with high reactivity in blood serum before the intervention and 21 days after the intervention. Method of measurement: C- Reactive protein measurement kit.

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Secondary

Measure	Time frame
Malondialdehyde( MDA). Timepoint: Malondialdehyde content is measured before and 21 days after consumption of yogurt enriched with fermented and non-fermented Spirulina Platensis. Method of measurement: diagnostic malondialdehyde assay kit.;Ferric Reducing Ability of Plasma( FRAP). Timepoint: Before starting consumption and 21 days after starting consumption of yogurt enriched with fermented and non-fermented spirulina platensis, the antioxidant capacity of total plasma is measured. Method of measurement: FRAP Detection Assay Kit.	—

Measure

Time frame

Malondialdehyde( MDA). Timepoint: Malondialdehyde content is measured before and 21 days after consumption of yogurt enriched with fermented and non-fermented Spirulina Platensis. Method of measurement: diagnostic malondialdehyde assay kit.;Ferric Reducing Ability of Plasma( FRAP). Timepoint: Before starting consumption and 21 days after starting consumption of yogurt enriched with fermented and non-fermented spirulina platensis, the antioxidant capacity of total plasma is measured. Method of measurement: FRAP Detection Assay Kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAnoosheh Sharifan

Islamic Azad University

a_sharifan2000@yahoo.com+98 21 4486 5154

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026