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Best Choice between aripiprazole and risperidone in methamphetamine psychosis

Comparison of the effectiveness of aripiprazole and risperidone on the psychotic symptoms of methamphetamine use

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220103053615N1
Enrollment
64
Registered
2022-04-18
Start date
2022-04-30
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metamphetamin induced psychotic disorder. Other stimulant abuse with stimulant-induced psychotic disorder

Interventions

Intervention 1: intervention group 1:taking Risperidone oral tablet, 2-8mg over 24 hours variable dosage decided by clinical care giver, daily, for at least a month and abidi pharma brand. Interventio

Sponsors

University of social welfare and rehabilitation sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Men and women with written informed consent to enter the trial At least one Positive and Negative Syndrome Scale score equal or greater than 4 Methamphetamine use in less than 4 weeks leading to admition No other substance dependencies except for Tobacco diagnosis of Metamphetamin induced psychotic disorder according to Diagnostic and Statistical Manual of Mental Disorders, 5th Edition

Exclusion criteria

Exclusion criteria: Sever nonpsychiatric condition in which Risperidone or Aripiprazole are contraindicated Aripiprazole or Risperidone Allergies Active suicidal or homicidal thoughts Comorbid mood or anxiety disorders Pregnant or nursing women or high suspicion of pregnancy Psychiatric medication use in last 4 weeks other than Benzodiazepines

Design outcomes

Primary

MeasureTime frame
Score of Positive and Negative Syndrome Scale. Timepoint: Days: 0, 7, 28 after medication. Method of measurement: Positive and Negative Syndrome Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepehr Mazloomi Koohbanani

University of social welfare and rehabilitation sciences

sep.mazloomi@uswr.ac.ir+98 21 7173 2832

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026