Liver metastasis. Secondary malignant neoplasm of liver and intrahepatic bile duct
Conditions
Interventions
Intervention group: Patients with gastrointestinal cancers who have liver metastases and need local treatment, but surgery and radiotherapy are not possible for them, are included in the study. For th
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Gastrointestinal cancer patients who suffers from multiple liver metastasis with size lesser than 4 cm Inoperable metastatic lesions Inability to radiation therapy of metastatic lesions Survival of at least 3 months is conceivable for the patient. Lesions near to main liver vessels Lesions near to main liver biliary tracts
Exclusion criteria
Exclusion criteria: Recurrence in lesser than 4 weeks after recent surgery, chemotherapy or radiation therapy Pregnancty INR more than one and a half times control Platelet lesser than 100,000 Absolute neutrophil count lesser than 1500 Having defibrillator, pace maker or suffering from cardiac arrhythmia Karnofsky performance status score 2 or more Chronic lung disease, lung fibrosis, lung failure
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The amount of liver enzymes. Timepoint: The amount of liver enzymes are measured at entry, one month and three months after the intervention. Method of measurement: Blood sample. | — |
Primary
| Measure | Time frame |
|---|---|
| Tumor marker (CEA). Timepoint: Tumor marker is measured at entry, one month and three months after the intervention. Method of measurement: Blood sample.;Size of tumor. Timepoint: Tumor size is measured at entry, one month and three months after the intervention. Method of measurement: Based on MRI of liver. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSepideh Mansouri
Tehran University of Medical Sciences
Outcome results
None listed