The effect of magnesium and vitamin E supplementation on hormonal status and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome referred to Nahal Infertility Treatment Center, Gorgan in 2021

The effect of magnesium and vitamin E supplementation on hormonal status and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220102053603N1

Enrollment

Registered

2022-03-14

Start date

2022-04-04

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hormonal status and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: 250 mg magnesium oxide per day (Twenty First Century Pharmaceutical Company, AZ, USA) plus 400 international units of vitamin E per day (Zahravi Pharmaceutical Comp

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Definitive diagnosis of PCOS based on Rotterdam criteria Age 18 to 40 years

Exclusion criteria

Exclusion criteria: Pregnancy Adrenal hyperplasia Androgen-secreting tumors Hyperprolactinemia Thyroid dysfunction Diabetes Receiving antioxidant and anti-inflammatory supplements 3 months before the start of the study

Design outcomes

Primary

Measure	Time frame
Hormonal status and biomarkers of inflammation and oxidative stress. Timepoint: 12 weeks after taking the supplement. Method of measurement: Laboratory.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGorgan University of Medical Sciences

Gorgan University of Medical Sciences

ykml@yahoo.com+98 17 3220 2565

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026