Fentanyl induced Cough. Cough
Conditions
Interventions
Intervention 1: Intervention group No.1: The group receiving 1mg / kg intravenous lidocaine 2%(100mg/5ml, Caspian,Tamin,RASHT.IRAN) 3 minutes before intravenous fentanyl ( fentanyl citrate,0.5mg/10ml
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: aged 18 to 60 years, with and with, who any gender ASA 1 or 2 referred to Firoozgar and Hazrat Rasul-e Akram hospitals and are candidates for elective surgery that lasts more than an hour in the period of April 2022 to June 2022
Exclusion criteria
Exclusion criteria: Preoperative pulmonary emphysema Bronchial asthma History of upper respiratory infection during the last 2 weeks Smoking Hypertension Coronary artery disease Has a chronic cough that makes it difficult to diagnose fentanyl-induced cough High pressure inside the eyes, brain or abdomen Taking anti-anxiety and anti-depressant drugs before surgery Taking anti-cough medicines (codeine, dextromethorphan, baclofen, steroids or bronchodilators) during the last week BMI above 28 kg/m2 History of chronic opioid use Taking cough medicines (ACEI & ABR) History of GERD or peptic ulcer History of kidney or liver disease Pregnancy or breastfeeding Known allergy to fentanyl or ketorolac G6PD deficiency disease High risk of GIB Patient reluctance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough. Timepoint: Within 90 seconds of fentanyl injection. Method of measurement: observation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough Intensity. Timepoint: Within 90 seconds of fentanyl injection. Method of measurement: Observation.;Cough start time. Timepoint: Within 90 seconds of fentanyl injection. Method of measurement: Stopwatch. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Tahzibi
Iran University of Medical Sciences
Outcome results
None listed