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The effect of propolis supplementation in hemodialysis patients

The effect of 8 weeks of aerobic exercise with propolis supplementation on biomarkers of oxidative stress in hemodialysis patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220102053595N1
Enrollment
60
Registered
2022-02-17
Start date
2022-02-19
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage renal disease. Chronic kidney disease, stage 5

Interventions

Intervention 1: Intervention group: the first group received 500 mg of propolis per day, 2 capsules containing 250 mg Propolis extract, 1 capsule before lunch, and 1 capsule before dinner, with 3 day

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: An age range of 18 to 65 years ESRD patients on hemodialysis treatment Perform hemodialysis 3 days a week Absence of any physical abnormalities or bone diseases that interfere with their physical activity Willingness to participate in research

Exclusion criteria

Exclusion criteria: BMI above 30 kg/m Disease (gallstones, cancer, and acute disease) Acute heart accident in the past year Taking any medicine outside the routine treatment protocol of hemodialysis patients Use of oral and injectable nutritional supplements except nephrovit and iron supplements according to the protocol Any allergy to honey and its compounds Leaving the patient with his/her personal consent Smoking, drug addiction or alcohol consumption

Design outcomes

Primary

MeasureTime frame
Malondialdehyde. Timepoint: At the beginning and end of the study. Method of measurement: kit.;Total antioxidant capacity. Timepoint: At the beginning and end of the study. Method of measurement: kit.;Systolic blood pressure. Timepoint: At the beginning and end of the study. Method of measurement: Mercury manometers.;Diastolic blood pressure. Timepoint: At the beginning and end of the study. Method of measurement: Mercury manometers.;Nutritional status. Timepoint: At the beginning and end of the study. Method of measurement: Food recall and 3-day food record questionnaires.;Anthropometric indicators. Timepoint: At the beginning and end of the study. Method of measurement: Weighing scale, Tape measure, BIA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSina Hamidi pour

Islamic Azad University

hamidipour.sina.nu@mshdiau.ac.ir+98 51 3661 3379

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026