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Comparison between microneedling plus topical tranexamic acid and microneedling in patients with macular amyloidosis

Comparison between microneedling plus topical tranexamic acid and microneedling in patients with macular amyloidosis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220101053588N1
Enrollment
22
Registered
2022-01-24
Start date
2022-01-12
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Amyloidosis. Other amyloidosis

Interventions

Intervention 1: Intervention group: First, all patients who have the criteria to enter the Survey, informed i consent to participate in the study is obtaibed. Prior to treatment, any contamination is

Sponsors

Skin Research Center Of Shahid Beheshti Universiy Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18-60 Confirming the diagnosis of macular amyloidosis by a dermatologist bilateral macular amyloidosis on trunk and extremities Patients with skin type 2_4 Fitzpatrick Filling out the informed consent form

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Past history of keloid formation Presence of active acne on site of macular amyloidosis Other skin disorders Hypersensitivity to lidocaine Application of other topical medications in the past month

Design outcomes

Primary

MeasureTime frame
Clinical improvement of pigmentation. Timepoint: first session and two weeks after final session. Method of measurement: comparison of photos by 2 dermatologist and fotofinder device.;Pigmentation pattern. Timepoint: first session and two weeks after final session. Method of measurement: checking for rippling.;Patient satisfaction. Timepoint: two weeks after final session. Method of measurement: asking the patient.

Secondary

MeasureTime frame
Side effects. Timepoint: Since 2weeks after starting of the treatment, till 2 weeks after the last session. Method of measurement: Asking the patient, examination by dermatologist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Gheisari

Shahid Beheshti University of Medical Sciences

mgheisari@sbmu.ac.ir+98 21 25719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026