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Acupuncture and Cognitive Impairment in MS

Comparison of the Effectiveness of Acupuncture with Sham Acupuncture on Cognitive Functioning in Multiple Sclerosis Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220101053582N1
Enrollment
60
Registered
2022-01-04
Start date
2022-01-21
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group: The acupuncture group will receive acupuncture treatment 2 times per week for 12 weeks (24 sessions). Patients will receive their routine medications for MS. Major

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients with relapsing-remitting multiple sclerosis Expanded disability status scale (EDSS) = 5.5 Age 18 to 55 years Sign the written informed consent

Exclusion criteria

Exclusion criteria: History of cognitive impairment caused by other chronic or malignant disease Acute relapse or corticosteroid therapy in the last 30 days before inclusion Previous use of acupuncture or using any herbal or other alternative treatments Pregnancy or breastfeeding

Design outcomes

Primary

MeasureTime frame
Score of cognitive functioning assessment test. Timepoint: Measurement of cognitive function before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Brief International Cognitive Assessment for multiple sclerosis (BICAMS) questionnaire.

Secondary

MeasureTime frame
Score of Sleep Quality index. Timepoint: Before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Pittsburgh Sleep Quality index questionnaire.;Score of psychological problems checklist. Timepoint: Before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Symptom Checklist 90- Revised questionnaire.;Score of fatigue severity. Timepoint: Before the intervention and after 24 sessions of acupuncture during 12 weeks. Method of measurement: Fatigue severity scale questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaezeh Khodaie

Tehran University of Medical Sciences

faezeh.khodaie@gmail.com+98 21 6634 8571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026