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Effect of intra-canal cryotherapy on postoperative pain in single-visit endodontic retreatment: randomized clinical trial

Effect of intra-canal cryotherapy on postoperative pain in single-visit endodontic retreatment: randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211231053574N1
Enrollment
46
Registered
2022-12-19
Start date
2022-09-23
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative pain after a single visit non-surgical root canal retreatment.

Interventions

Intervention 1: Intervention group: Patients who undergo non-surgical root canal retreatment in one visit, at the end of the treatment, and before the obturation, the root canals are irrigated with no

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients should be classified as ASA I or ASA II in terms of systemic health The teeth should have no spontaneous pain Teeth with periapical lesions or teeth with clear evidence of leakage.

Exclusion criteria

Exclusion criteria: Teeth that cannot create a glide path to the apical foramen due to canal blockage or previous treatment errors Patients with chronic periapical abscess, sinus tract, internal or external resorption, periodontal problems Pregnant patients Patients with a history of trauma Patients with Temporomandibular disorders Patients who cannot take NSAIDs Patients who have a history of taking antibiotics, analgesics and anti-inflammatory agents before treatment Patients who smoke more than 10 cigarettes a day

Design outcomes

Primary

MeasureTime frame
Post-operative pain on the scale of Numerical Rating Scale. Timepoint: 6h-18h-24h-48h-72h-7d. Method of measurement: Numerical Rating Scale on the scale of 0-100.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Mahdi Kiafar

Tehran University of Medical Sciences

m-kiafar@razi.tums.ac.ir+98 21 6636 9439

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026