The effect of exercise and bee propolis supplement on type 2 diabetes

The effect of eight weeks of combined training (resistance-aerobic) and propolis supplementation on serum levels of adipolin (CTRP12) and secretory protein associated with secretory curvature (SFRP5) and Interleukin 6 (IL6) and glycemic indexes in women with type 2 diabetes with dyslipidemia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211229053561N2

Enrollment

Registered

2022-01-29

Start date

2022-02-04

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: Intervention group: The first intervention group, combined training + placebo (simultaneous intervention of combined training, which includes 20 minutes of aerobic training and 45 minu

Eligibility

Sex/Gender

Female

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Confirmation of type 2 diabetes (fasting blood sugar greater than 126 mg / dL, oral glucose tolerance test equal to or greater than 200 mg / dL, glycosylated hemoglobin 5.6% or higher) Body mass index between 27 Up to 35, age 40 to 60 years

Exclusion criteria

Exclusion criteria: Insulin use, having cardiovascular disease, musculoskeletal disease, liver disease, kidney disease, thyroid disorder, having a history of regular physical activity for at least the last six months

Design outcomes

Primary

Measure	Time frame
Interleukin 6. Timepoint: Before the intervention and 48 hours after the intervention. Method of measurement: Biochemical and laboratory methods.;Adipolin. Timepoint: Before the intervention and 48 hours after the intervention. Method of measurement: Biochemical and laboratory methods.;Secreted frizzled-related protein 5. Timepoint: Before the intervention and 48 hours after the intervention. Method of measurement: Biochemical and laboratory methods.	—

Measure

Time frame

Interleukin 6. Timepoint: Before the intervention and 48 hours after the intervention. Method of measurement: Biochemical and laboratory methods.;Adipolin. Timepoint: Before the intervention and 48 hours after the intervention. Method of measurement: Biochemical and laboratory methods.;Secreted frizzled-related protein 5. Timepoint: Before the intervention and 48 hours after the intervention. Method of measurement: Biochemical and laboratory methods.

—

Secondary

Measure	Time frame
Fasting blood glucose. Timepoint: Before and after the protocol. Method of measurement: Mg /dL by blood test.;Triglyceride. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.;Low density lipoprotein cholesterol. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.;High-density lipoprotein cholesterol. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.;Insulin. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.	—

Measure

Time frame

Fasting blood glucose. Timepoint: Before and after the protocol. Method of measurement: Mg /dL by blood test.;Triglyceride. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.;Low density lipoprotein cholesterol. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.;High-density lipoprotein cholesterol. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.;Insulin. Timepoint: Before and after the protocol. Method of measurement: Laboratory and biochemical methods.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh moayedi

Islamic Azad University of Khorasgan Branch

Fatemeh_m8040@yahoo.com+98 71 3632 2954

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026