Comparison of the effect of intravenous meperidine injection with dexamethasone and midazolam on shivering after orthopedic surgery

Comparison of the effect of intravenous injection of meperidin with dexamethasone and midazolam onpostoperative shivering in patients recovering from general anaesthesia in post orthopedic surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211226053537N1

Enrollment

120

Registered

2022-01-23

Start date

2022-02-20

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering after surgery.

Interventions

Intervention 1: Intervention group 1: participants will received meperidine (Exire, Iran)at a dose of 0.4 mg per kg. Intervention 2: Intervention group2: participants will received dexamethasone (Albo

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients undergoing elective orthopedic surgery At least 8 hours of fasting Ages between 18 and 65 years ASA class 1,2

Exclusion criteria

Exclusion criteria: hypothermia hyperthermia

Design outcomes

Primary

Measure	Time frame
Shivering after general anesthesia. Timepoint: In the meperidine group and the midazolam group; 2 minutes and in the dexamethasone group 5 minutes after injection. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Cheraghali

Karaj University of Medical Sciences

cheraghalimaryam@yahoo.com+98 21 2275 2546

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026