Effect of Synbiotic on reducing insulin resistance in overweight or obese children

The effect of Synbiotic on reducing insulin resistance in overweight or obese children

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211226053529N1

Enrollment

Registered

2021-12-31

Start date

2021-12-22

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Overweight and obesity

Interventions

Intervention 1: Intervention group: Children receive 1 sachet of probiotic daily (Kidi Lact, manufactured by Zist Takhmir Company, Iran) for 8 weeks. Intervention 2: Control group: Children received o

Eligibility

Sex/Gender

All

Age

4 Years to 18 Years

Inclusion criteria

Inclusion criteria: Age range between 4 -18 years Obese or overweight children: Obese children, children with a BMI of more than 95% and overweight children, children with a BMI between 85-95% Children with insulin resistance (HOMA-IR : > 2.5 = Positive for IR)

Exclusion criteria

Exclusion criteria: Children who developed obesity following synromic disorder or endocrine disorders Physical disability Taking corticosteroids Treated with metformin Under special treatment or diet Acute pancreatitis History of allergies

Design outcomes

Primary

Measure	Time frame
Insulin Resistance level. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: HOMA-IR.Index (µU/ml).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRana Drodian

Iran University of Medical Sciences

rohani.f@iums.ac.ir+98 21 2304 6253

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026