Retinopathy of Prematurity. Retinopathy of prematurity
Conditions
Interventions
Intervention 1: Intervention group: Babies receive melatonin softgel (Nutralab under license of Canada) daily at dosage of 3 mg/ kg/day until 37 weeks. Intervention 2: Control group: This group of neo
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 7 Days
Inclusion criteria
Inclusion criteria: Parents satisfaction to participate in the study Premature newborns under 34 weeks Lack of congenital anomalies Lack of genetic disorder, metabolic disorder or suffering from TORCH Lack of intraventricular hemorrhage (grade 3 and 4)
Exclusion criteria
Exclusion criteria: Intraventricular hemorrhage (grade 3 and 4) during patients follow up Incidence of gastrointestinal complications such as NEC during treatment if it is not possible to take the medicine orally. Taking less than 14 days of melatonin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stopping of abnormal blood vessels formation in the retina. Timepoint: End of 37 weeks and end of 44 weeks. Method of measurement: Examination by retina fellowship and with ophthalmoscope. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Khalilian
Iran University of Medical Sciences
Outcome results
None listed