Comparing open and closed thread surgical techniques in carpal tunnel syndrome

Comparing the surgical outcomes of carpal tunnel syndrome treatment between open carpal tunnel release (OCTR) and thread carpal tunnel release (TCTR)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211225053519N2

Enrollment

Registered

2022-01-10

Start date

2022-01-21

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome. Mononeuropathies of upper limb

Interventions

Intervention 1: Intervention group: In the open surgery group, after a 1 cm incision, the proximal wrist groove will open and after exposing the median nerve, the guiding groove will pass from inside

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Clinical symptoms of carpal tunnel syndrome Positive Phalen Test Mild cases of carpal tunnel syndrome (sensory nerve action potential (SNAP) more than 3.6 m.s in the electrodiagnostic study) Moderate cases of carpal tunnel syndrome (sensory nerve action potential (SNAP) more than 3.6 m.s and compound muscle action potential (CMAP) more than 4.2 m.s in the electrodiagnostic study) Lack of responses to non-surgical treatments

Exclusion criteria

Exclusion criteria: Thenar atrophy Severe cases of carpal tunnel syndrome (lack of sensory nerve action potential (SNAP) and compound muscle action potential (CMAP) and nerve conduction velocity (NCV) less than 40 m/s across the wrist) Neurodegenerative or demyelinating diseases History of surgical treatment for carpal tunnel syndrome in last 6 months History of corticosteroid injection for carpal tunnel syndrome in last 6 months Lack of consent for inclusion into the study

Design outcomes

Primary

Measure	Time frame
Scar length in centimeter. Timepoint: 3 month after the surgery. Method of measurement: Direct observation.;Postsurgical pain. Timepoint: One day after the surgery. Method of measurement: Visual analog score (VAS).;Operation time in minute. Timepoint: During the operation. Method of measurement: Assessing the minutes by clock.;Two point discriminations in thumb and index fingers. Timepoint: One month after the surgery. Method of measurement: Sensing two point discriminations based on millimeters.;Monofilament test. Timepoint: One month after the operation. Method of measurement: Monofilament assessment.;Electrodiagnostic assessment. Timepoint: One month after the operation. Method of measurement: Electrodiagnostic study.	—

Measure

Time frame

Scar length in centimeter. Timepoint: 3 month after the surgery. Method of measurement: Direct observation.;Postsurgical pain. Timepoint: One day after the surgery. Method of measurement: Visual analog score (VAS).;Operation time in minute. Timepoint: During the operation. Method of measurement: Assessing the minutes by clock.;Two point discriminations in thumb and index fingers. Timepoint: One month after the surgery. Method of measurement: Sensing two point discriminations based on millimeters.;Monofilament test. Timepoint: One month after the operation. Method of measurement: Monofilament assessment.;Electrodiagnostic assessment. Timepoint: One month after the operation. Method of measurement: Electrodiagnostic study.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Amin Shahrbaf

Iran University of Medical Sciences

Aminshahrbaf41@gmail.com+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026