Condition 1: Major depressive disorder, single episode, moderate. Condition 2: Major depressive disorder, single episode, mild. Condition 3: Major depressive disorder, recurrent, mild. Condition 4: Major depressive disorder, recurrent, moderate. Condition 5: Major depressive disorder, single episode, severe without psychotic features. Condition 6: Major depressive disorder, recurrent severe without psychotic features. Condition 7: Bipolar disorder, current episode depressed, mild or moderate sev
Conditions
Interventions
Intervention 1: Intervention group: 2 months of standard treatment (sertraline) + inhalation of one puff per day of 5% clove essential oil (diluted in ethanol) applied to the collar of the shirt + pla
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 18 to 65 years A patient with major depressive disorder or bipolar disorder in the depressive episode
Exclusion criteria
Exclusion criteria: Existence of psychotic symptoms Cognition disorders Anxiety disorders Schizophrenia Antisocial personality disorder Mental retardation Dementia Pregnancy Lactation Explicit suicidal ideation History of allergy to herbal drugs Having a proven problem with the sense of smell
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression rate. Timepoint: Weeks 0, 4 and 8 after the start of the intervention. Method of measurement: Hamilton Depression Inventory 17 items and Clinical Global Impression Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Javan
Hamedan University of Medical Sciences
Outcome results
None listed