Acute Mountain Sickness. Other effects of high altitude
Conditions
Interventions
Intervention 1: Intervention group1: On the day of the ascent, the mountaineers will start their ascent from an altitude of 1900 meters from the first station of the Tochal cable car at 8:00 AM. The s
Sponsors
Razi University
Eligibility
Sex/Gender
Male
Age
20 Years to 29 Years
Inclusion criteria
Inclusion criteria: Healthy men 20 to 29 years Lived for at least 6 months in Tehran Body mass index 18.5 to 24.9 (kg.m2) At least two weeks have passed since the second dose of Corona vaccine was given
Exclusion criteria
Exclusion criteria: Having any acute or chronic illness Suffering from psychological or skeletal disorders smoking Climbing to altitudes of more than 2500 meters in the two months before the start of the research Blood donation in the two months before the start of the research Flight by aircraft in the two months prior to the start of the research History of high-altitude sports such as mountaineering, skiing and air sports
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting heart rate changes. Timepoint: 4 p.m, the day before the ascent, at the first station of the cable car before the ascent, as well as at stations two and five, at the hotel at high altitude after a 10-minute rest, one hour after arriving at the hotel, at 4 p.m the next day (before returning to low height). Method of measurement: Pulse meter.;Resting blood pressure changes. Timepoint: 4 p.m, day before the ascent, 4 p.m, day of the ascent (one hour after arriving at the hotel at high altitude), 4 p.m, the next day (before returning to low altitude). Method of measurement: sphygomanometer.;Anxiety levels. Timepoint: The day before the ascent at 4:00 p.m, the day of the ascent about 2 and 6 hours after entering the hotel at high altitude and also the next morning before returning to low altitude. Method of measurement: Anxiety Disorders Questionnaire.;Changes in arterial blood oxygen saturation levels. Timepoint: 4 p.m, the day before the ascent, at the first station of the cable car before the ascent, as well as at stations two and five, at the hotel at high altitude after a 10-minute rest, one hour after arriving at the hotel, at 4 p.m the next day (before returning to low height). Method of measurement: By pulse oximeter device.;Acute Mountain Sickness. Timepoint: About 2 and 6 hours after arrival at the hotel at high altitude as well as the next morning. Method of measurement: Lake Louise Score.;Changes in serum interleukin 6 levels. Timepoint: 4 p.m, day before the ascent, 4 p.m, day of the ascent (one hour after arriving at the hotel at high altitude), 4 p.m, the next day (before returning to low altitude). Method of measurement: Blood sampling.;Changes in serum endothelin 1 levels. Timepoint: 4 p.m, day before the ascent, 4 p.m, day of the ascent (one hour after arriving at the hotel at high altitude), 4 p.m, the next day (before returning to low altitude). Method of measurement: Blood sampling.;Changes in serum Tumor Necrosis Factor-a levels. Timepoint: | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSahba Ariandoost
Razi University
Outcome results
None listed