Condition 1: post cabg pericardial effusion. Condition 2: post cabg pericarditis.
Conditions
Interventions
Intervention 1: Intervention group: Patients in the intervention group will be given 0.5 mg of colchicine every 12 hours for 48 hours before surgery and 0.5 mg daily orally until discharge if they wei
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: All patients referred to Fatemeh Zahra Heart Hospital with coronary artery disease who are candidates for coronary artery bypass graft surgery
Exclusion criteria
Exclusion criteria: Patients over 80 years old Presence of pericardial effusion in preoperative trans-thoracic echo Existence of pleural effusion in CXR standing before surgery Chronic lung, liver disease (known case of liver disease or LFT more than 3 times normal) and kidney disease (known case of kidney disease or Cr> 2.5) Other heart surgeries at the same time as coronary artery bypass grafting Patients who was allergic reaction to colchicine or given colchicine in any way are contraindicated pregnant patients Patients receiving colchicine before starting of study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pericardial effusion. Timepoint: Before discharg and 14 days after surgery. Method of measurement: echocardiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pleural effusion. Timepoint: Before discharge and 14 days after surgery. Method of measurement: echocardography.;Pericarditis. Timepoint: Before discharge and 14 days after surgery. Method of measurement: Echocardiography and clinical history. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohamad Hosein Taghvayi
Mazandaran University of Medical Sciences
Outcome results
None listed