Bipolar disorder. Bipolar disorder, current episode depressed, mild or moderate severity
Conditions
Interventions
Intervention 1: Intervention group: 30 patients with bipolar disorder, in addition to their usual treatment, will receive 2 omega 3 capsules daily (made by Barij Pharmaceutical Company), each capsule
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: The involvement with bipolar disease Patients with minimum six months after onset of disease Informed and freely consent for participation in the design by patient and family members. The lack of receiving omega-3 supplement several months before of participation in the study The lack of programmed surgery in three months future The lack of consumption of drugs interfering with omega-3 such as anticoagulant drugs The lack of high blood pressure The lack of alcohol and drugs
Exclusion criteria
Exclusion criteria: The change in drug dose and type Sensitive reaction against omega-3 The consumption of lesser than 80% supplement The involvement with inflammatory and infectious diseases Withdrawal of the study for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean of interleukin 6. Timepoint: At the beginning of the study (before the intervention) and 60 days after the start of omega-3 supplementation. Method of measurement: Commercial Kit / ELISA.;Mean of alpha tumor necrosis factor. Timepoint: At the beginning of the study (before the intervention) and 60 days after the start of omega-3 supplementation. Method of measurement: Commercial Kit / ELISA.;Depression score on the Hamilton questionnaire. Timepoint: At the beginning of the study (before the intervention) and 60 days after the start of omega-3 supplementation. Method of measurement: Hamilton questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHadi Eslahi
Zahedan University of Medical Sciences
Outcome results
None listed