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Comparison of the effects of Cetirizine and Desloratadine on the symptoms of chronic spontaneous urticarial

Comparison of the effects of Cetirizine and Desloratadine on the symptoms of chronic spontaneous urticarial and quality of life

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211219053449N1
Enrollment
180
Registered
2022-10-16
Start date
2022-10-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic urticaria. Urticaria

Interventions

Intervention 1: Intervention group 1: prescription of cetirizine tablets from Abidi pharmaceutical company in 4 times the standard dose for 2 weeks. Intervention 2: Intervention group 2: Administratio

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The purpose of the study will be explained to all patients and written informed consent will be obtained. CSU patients with a history of chronic spontaneous urticaria for at least six weeks during the last three months who did not respond to standard doses of second-generation antihistamines the illness was not controlled according to the disease questionnaire.

Exclusion criteria

Exclusion criteria: Pregnancy Drug-induced urticaria Vasculitis urticaria Hereditary angioedema Colitis urticaria Physical urticaria cold urticaria

Design outcomes

Primary

MeasureTime frame
UCT questionnaire score: assessment of pruritus and urticaria symptoms. Timepoint: before and after 14 days of taking the drug. Method of measurement: UCT questionnaire.;CU-QoL questionnaire: assessment of quality of life. Timepoint: At the beginning of the study and 2 weeks after taking the drug. Method of measurement: Chronic Urticaria-Quality of Life Questionnaire (CU-QoL).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Khoshkhui

Mashhad University of Medical Sciences

KhoshkhuiM@mums.ac.ir+98 51 3840 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026