The effect of herbal products of Iranian traditional medicine (Ziziphus jujuba, Glycyrrhiza glabra, and Cydonia oblonga) on the symptoms of patients with COVID-19

Investigating the effect of herbal products of Iranian traditional medicine (Ziziphus jujuba, Glycyrrhiza glabra, and Cydonia oblonga) on the symptoms of patients with COVID-19

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211218053445N1

Enrollment

146

Registered

2022-07-19

Start date

2022-07-22

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 disease. Coronavirus infection, unspecified

Interventions

Intervention 1: Intervention group: For these patients, the syrup made from Ziziphus jujube, Glycyrrhiza glabra, and Cydonia oblonga is prescribed orally in a daily dose of 32 grams (equivalent to 27

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Being between 18 and 75 years old Definite diagnosis of Covid-19 disease based on PCR test or lung CT scan

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding History of any allergy to product components Patient's hypercapnia Loss of consciousness

Design outcomes

Primary

Measure	Time frame
Fever duration. Timepoint: After the intervention. Method of measurement: Thermometer(length of days the patient has a fever).;Fever severity. Timepoint: After the intervention. Method of measurement: Thermometer.;Arterial oxygen saturation. Timepoint: After the intervention. Method of measurement: pulse oximeter.;Cough severity. Timepoint: After the intervention. Method of measurement: Cough Severity Index (CSI).	—

Measure

Time frame

Fever duration. Timepoint: After the intervention. Method of measurement: Thermometer(length of days the patient has a fever).;Fever severity. Timepoint: After the intervention. Method of measurement: Thermometer.;Arterial oxygen saturation. Timepoint: After the intervention. Method of measurement: pulse oximeter.;Cough severity. Timepoint: After the intervention. Method of measurement: Cough Severity Index (CSI).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hosein Manian

Babol University of Medical Sciences

Alimanian94@gmail.com+98 11 3219 4728

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026