The effect of varicocelectomy and mast cell stabilizer on sperm DNA fragmentation

effect of varicocelectomy and/or mast cells stabilizer on sperm DNA fragmentation in infertile patients with varicocele

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211217053436N1

Enrollment

123

Registered

2022-01-27

Start date

2020-08-29

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility caused by varicocele. Scrotal varices

Interventions

Intervention 1: Control group: In the control group, individuals undergo only varicocelectomy microsurgery and the outcome is evaluated after 3 months. (Surgery only). Intervention 2: First Interventi

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Infertile men due to varicocele (in reproductive age) Informed consent

Exclusion criteria

Exclusion criteria: Allergic reaction to drug Drug complication Leukocytospermia Azoospermia Diabetics

Design outcomes

Primary

Measure	Time frame
Sperm DNA fragmentation. Timepoint: Before intervention and 3 months after intervention. Method of measurement: DNA Fragmentation Index percentage.;Semen Analysis. Timepoint: Before intervention and 3 months after intervention. Method of measurement: Semen Analysis.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Akhavan Rezayat

Mashhad University of Medical Sciences

akhavanra@mums.ac.ir+98 51 3843 2256

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026