Herbal cream of borage, evening primrose, calendula, and leek versus topical mometasone 0.01% for atopic dermatitis

Efficacy of topical herbal cream formulation consisting of borage, evening primrose, calendula and, leeks versus topical mometasone 0.01% in the treatment of atopic dermatitis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211216053428N1

Enrollment

Registered

2022-02-22

Start date

2022-01-20

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis. Atopic dermatitis

Interventions

Intervention 1: Intervention group: topical herbal cream consisting of borage, evening primrose, calendula, and leeks daily for a month and tapered during the next month. Intervention 2: Control group

Eligibility

Sex/Gender

All

Age

7 Years to No maximum

Inclusion criteria

Inclusion criteria: Age >7 years SCORAD score <50

Exclusion criteria

Exclusion criteria: Accompanying physical illness Any physical illness preventing drug administration Treatment in the past 6 months Drug use or alcohol consumption in the past 6 months Pregnancy or lactation Lack of following up by the patient Severe drug hypersensitivity

Design outcomes

Primary

Measure	Time frame
Improvement in SCORing Atopic Dermatitis (SCORAD). Timepoint: Weeks 0, 4, 8, and 12. Method of measurement: SCORing Atopic Dermatitis (SCORAD).	—

Secondary

Measure	Time frame
Patient satisfaction with treatment. Timepoint: Weeks 4, 8, and 16. Method of measurement: 10-item visual analogue scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaeze Mousavi

Esfahan University of Medical Sciences

mousavi_faeze97@yahoo.com+98 31 5254 3385

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026