infertility. Female infertility associated with anovulation
Conditions
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Infertile women with polycystic ovarian syndrome (PCOS) based on the Rotterdam Criteria 20 to 35 years old Informed consent to participate in the study Minimum and maximum Infertility period: 1-5 year BMI less than 30 kg per square meter
Exclusion criteria
Exclusion criteria: Male factor Infertility Tubular infertility other types of ovarian cysts except PCO Endometriosis Premature ovarian failure (POF) and decreased ovarian reserve (DOR) Underlying and systemic disease and malignancy Breast disease such as breast cysts Liver, kidney, joint and rheumatic disorders Other diseases including metabolic diseases such as diabetes and endocrine disorders including uncontrolled hypothyroidism, hyperprolactinemia and Cushing's disease Taking herbal medicine during the last month Lack of cooperation to continue the study Severe allergy or drug complications Risk of Ovarian Ovulation Syndrome (OHSS) The entering The patient into a new treatment phase during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian follicle size. Timepoint: Before the intervention and during 10th to 12th of menstrual cycle (in case of lack of proper size of the ultrasound follicle on days 14-16 and finally 20-22 cycles) the first and second months after the intervention. Method of measurement: vaginal ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Numbers of dominant follicles. Timepoint: Before the intervention and during 10th to 12th of menstrual cycle (in case of lack of proper size of the ultrasound follicle on days 14-16 and finally 20-22 cycles)of the first and second month after the intervention. Method of measurement: vaginal ultrasound.;Endometrial thickness. Timepoint: Before the intervention and during 10th to 12th of menstrual cycle of the first and second month after the intervention. Method of measurement: vaginal ultrasound.;Endometrial pattern. Timepoint: Before the intervention and during 10th to 12th of menstrual cycle of the first and second month after the intervention. Method of measurement: vaginal ultrasound.;Chemical pregnancy. Timepoint: After the first delay in menstruation, the fourth week of the menstruation cycle. Method of measurement: Serum ?-hCG meausurment.;Clinical pregnancy. Timepoint: After a positive serum ?-hCG test, the fifth to sixth week of the menstruation cycle. Method of measurement: Observing fetal heart rate on ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMina Atharizadeh
Ghoum University of Medical Sciences
Outcome results
None listed