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The effect of exercise on fatigue in MS

The Effect of Aerobic-cognitive Combined Training on Inflammatory factors and Mental fatigue in Multiple Sclerosis Patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211214053407N1
Enrollment
45
Registered
2021-12-28
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group 1: Performing 8 weeks of aerobic-cognitive training called Brightonic training, which includes 2 sessions of approximately 40 minutes each week. Intervention 2: Inte

Sponsors

Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: The subjects used in this study will be patients with MS and all of them will use interferon. People with recurrent and clinically stable MS with a minimum of disability (EDSS) below 3 will be selected for this study. The age range of the subjects will be 20 to 50 years (based on the average age of the patients).

Exclusion criteria

Exclusion criteria: People with cardiovascular disease, diabetes, thyroid disorders, gout, and orthopedic restrictions Patients who have an attack 4 weeks before or during the project. No signing the consent form approved by the Research Ethics Committee

Design outcomes

Primary

MeasureTime frame
Determining the effect of Brightonic training on mental fatigue in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: Mental fatigue will be assessed by the MFIS Modified Fatigue Effect Questionnaire.;Determining the effect of Brightonic training on inflammatory factors in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: Inflammatory factors will be assessed by measuring the plasma levels of interleukin 17 and interleukin 4 and their ratios.

Secondary

MeasureTime frame
Determining the effect of Brightonic training on sleep quality in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: By the Petersburg Sleep Quality Questionnaire.;Determining the effect of Brightonic training on quality of life in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: By Vickery Quality of Life Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Farajnia

Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran

sfarajnia2020@gmail.com+98 21 2641 6337

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026