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Evaluation of leishmaniasis wound healing in topical treatment with 5% thyme gel versus intra lesional(IL) Glucantime treatment

Evaluation of the effectiveness of topical gel treatment containing standardized 5% hydroalcoholic extract of Zataria multiflora in comparison with intra lesional(IL) glucantime in the treatment of cutaneous leishmaniasis in human

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211211053349N1
Enrollment
80
Registered
2022-03-25
Start date
2021-12-25
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lesion of cutaneous Leishmaniasis. Cutaneous leishmaniasis

Interventions

Intervention 1: Intervention group: Topical thyme gel treatment 0.5 gram for 2 times a day with topical injection of Glucantime once a week for 8 weeks until complete wound healing. Intervention 2: C

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients must be 5 years old or older. The patient can be of both sexes. The number of wounds should not be more than 5. No sores on the face or ears. Affirmation of parasitic infection is required The patient has cutaneous leishmaniasis. The onset of their disease is less than 4 months

Exclusion criteria

Exclusion criteria: Pregnant women are excluded from the study. Patients with severe hypoglycemia are excluded from the study. Breastfeeding women are excluded from the study. Patients who have been treated with other methods (systemic Glucantime, combination therapy, etc.) patients who have been treated in other clinical trial

Design outcomes

Primary

MeasureTime frame
Wound healing. Timepoint: lesion diameter. Method of measurement: recurence.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila shirani Bidabadi

Kerman University of Medical Sciences

lshiranibidabadi@gmail.com+98 34 3132 5053

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026