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Comparison of the effect of minoxidil and spironolactone with minoxidil and finasteride in the treatment of Androgenic Alopecia

Comparative study of the combined effect of topical minoxidil and oral spironolactone with the combined effect of topical minoxidil and oral finasteride on female pattern and male pattern hair loss in women referred to Rasool Akram and Firoozgar hospitals in 1400-1401

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211210053343N1
Enrollment
60
Registered
2021-12-29
Start date
2022-01-05
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenic Alopecia. Androgenic alopecia

Interventions

Intervention 1: Intervention group 1: Patients in the first group use Minoxidil solution 2% once a day and Spironolactone (100 mg daily in two doses) for 4 months. Intervention 2: Intervention group 2

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: scalp involvement aged 15-45 years satisfaction to participate in the study ability to follow the patient based on the doctor's diagnosis normal hormonal tests

Exclusion criteria

Exclusion criteria: having an underlying disease history of polycystic ovary syndrome history of treatment in the last two months for the disease contraindications to the use of spironolactone or finasteride such as pregnancy and lactation concomitant use of drugs that may interact with the drugs under study

Design outcomes

Primary

MeasureTime frame
Severity of alopecia. Timepoint: At the beginning of the study, 2 and 4 months later. Method of measurement: based on Ludwig grade by patient s physician.;Qualitative and quantitative severity of alopecia. Timepoint: At the beginning of the study, 2 and 4 months later. Method of measurement: based on clinical and dermatoscopic images by a blind dermatologist.;The rate of improvement. Timepoint: 2 and 4 months after the beginning of the treatment. Method of measurement: based on patient satisfaction scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfsaneh Sadeghzadeh Bazargan

Iran University of Medical Sciences

afsaneh.sadeghzadeh@yahoo.com+98 21 6651 7341

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026