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Evaluation of efficacy and safety of furosemide in transurethral prostate resection in reducing postoperative hyponatremia : a randomized controlled trial

Evaluation of efficacy and safety of furosemide in transurethral prostate resection in reducing postoperative hyponatremia : a randomized controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211208053328N2
Enrollment
70
Registered
2022-07-30
Start date
2022-08-06
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyponatremia after TURP surgery. Encounter for surgical aftercare following surgery on the genitourinary system

Interventions

Intervention 1: Intervention group: Immediately before the anesthesia induction, they will receive intravenous 40 mg of furosemide (Ampule Lasix, 40mg/4ml, Sanofi, India). This group also receives the

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Patients have standard indication for TURP (Transurethral resection of the prostate)(frequent urinary retention, bilateral hydronephrosis with the probability of kidney damage, frequent urinary tract infection because of high post-void residual, Gross and severe hematuria, severe urinary symptoms in BPH (benign prostatic hyperplasia) that is resistant to treatment) Normal renal function (Normal blood urea nitrogen and creatinine)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sodium level of the serum. Timepoint: Before surgery, one hour after surgery and 24 hours after surgery. Method of measurement: Audicom AC9800 Automatic Electrolyte Analyzer.

Secondary

MeasureTime frame
Potassium level of the serum. Timepoint: Before surgery, one hour after surgery and 24 hours after surgery. Method of measurement: Audicom AC9800 Automatic Electrolyte Analyzer.;Creatinine level of the serum. Timepoint: Before surgery, one hour after surgery and 24 hours after surgery. Method of measurement: Creatinin Jaffe kit, Biorexfars company.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Bahrami Samani

Esfahan University of Medical Sciences

Bahrami.hossein1993@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026