The effect of intravenous Tranexamic acid on postoperative bleeding in patients with shaft femoral fractures

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211208053326N1

Enrollment

Registered

2022-01-30

Start date

2022-01-20

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

shaft femoral fractures. Fracture of shaft of femur

Interventions

Intervention 1: Intervention group: Before the start of surgery, 10 milligram in kilogram of tranexamic acid (Tranexip in Iran -Caspian Company, 100 milligram in kilogram) will be given by slow intrav

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients who are candidates for shaft and distal femoral fractures Lack of sensitivity to tranexamic acid No history of cerebral ischemia Lack of hematuria Surgery that lasts less than 3 hours

Exclusion criteria

Exclusion criteria: hypertension history of cerebral ischemia anemia take any anticoagulants for 5 days before surgery platelets less than 150,000 before surgery history of myocardial ischemia underlying diseases such as kidney disease

Design outcomes

Primary

Measure	Time frame
Bleeding amount. Timepoint: From 6 hours and 24 hours after surgery. Method of measurement: Millilitre.;Hemoglobin amount. Timepoint: Before and after surgery. Method of measurement: Blood test.;Hematocrit amount. Timepoint: Before and after surgery. Method of measurement: Blood test.;Mortality. Timepoint: End of study. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohsen Parsi Kameneh

Arak University of Medical Sciences

parsi70@yahoo.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026