Skip to content

The role of transcranial direct current stimulation on emotional bias, mind-wandering and affect for patients with depression disorder

The role of transcranial direct current stimulation on emotional bias, mind-wandering and affect for patients with depression disorder

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211207053315N1
Enrollment
23
Registered
2021-12-29
Start date
2021-04-09
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depression disorder. Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group: Left anode/Right cathode intervention
In this intervention, the positive electrode (anode) is placed on the left dorsolateral prefrontal cortex (DLPFC) , which leads to increased neuronal activity, and the negative electrode (cathode) is
In this intervention, the negative electrode (cathode) is placed on the left dorsolateral prefrontal cortex (DLPFC) , which leads to a decrease in neuronal activity in this area, and the positive elec
In this intervention, the anode and cathode electrodes are placed on the subject's head for 15 minutes like a real stimulus, but no electric current enters the subject except for the first 30 seconds

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: psychiatric diagnosis of depressive disorder Age range 20-40 years Being right-handed

Exclusion criteria

Exclusion criteria: any serious medical conditions such as a history of trauma or head surgery History of seizures Existence of intracranial implants Pregnancy acute vision problems

Design outcomes

Primary

MeasureTime frame
Emotional bias. Timepoint: Simultaneously with the intervention. Method of measurement: the score that the subject has tested in the computer test of emotional faces (Dot-probe).;Mind wandering. Timepoint: Simultaneously with the intervention. Method of measurement: the score that the subject has tested in the computer test of SART.;Affect. Timepoint: Before and after each stimulation session. Method of measurement: the score that the subject achieves on the PANAS positive and negative emotion scale.

Secondary

MeasureTime frame
Side effects of tDCS: Headache, dizziness, burning, itching. Timepoint: Immediately after the actual stimulation and sham condition. Method of measurement: TDCS Side Effects Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam.Majidinezhad

Iran University of Medical Sciences

maryam.majidinezhad001@gmail.com0098 21 66551655-60

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026