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Evaluation of the Effect of Two Different Methods of Anesthesia on Pain and Nausea and Vomiting in Children with Cancer

Evaluation and Comparison of the Effectiveness of General Anesthesia with Souffleran and Propofol on Nausea, Vomiting and Agitation after Bone Marrow Aspiration and Intrathecal Injection in Children with Cancer Referred to Bahrami Hospital.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211206053305N1
Enrollment
30
Registered
2022-10-10
Start date
2022-06-22
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Agitation and Nausea and Vomiting.

Interventions

Intervention 1: Intervention Group: Patients in the First Group will Receive 35 mg / kg Fentanyl Before Induction of Anesthesia. In the Next Step, They will be Induced Anesthesia by Receiving 8% Souff

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 10 Years

Inclusion criteria

Inclusion criteria: All Children Between the Ages of 1 and 10 Have a Diagnosis of Cancer that Requires General Anesthesia for Intrathecal Injection and Bone Marrow Biopsy

Exclusion criteria

Exclusion criteria: Dissatisfaction of the Patient or her/his legal Guardian to Participate in the Study Lack of Proper Cooperation of the Patient or his/her legal Guardian History of Any Past or Present lung Disease or Involvement History of Past or Present Respiratory Distress History of Any Past or Present Cardiovascular Disease Simultaneous Involvement of Any Disorders leading to Nausea and Vomiting History of Any Drug Allergies, Allergies to Eggs, Soy History of Convulsion

Design outcomes

Primary

MeasureTime frame
Severity of Nausea and Vomiting. Timepoint: Post Operative Nausea and Vomiting will be Measured After Transferring Patients to the Recovery Room. Method of measurement: Examination.;Agitation. Timepoint: Pediatric Anesthesia Emergence Delirium Score will be Measured after Transferring Patients to the Recovery Room. Method of measurement: Pediatric Anesthesia Emergence Delirium Score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Mahsa Hosseini

Tehran University of Medical Sciences

Smahsahosseini1376@gmail.com+98 11 5216 1764

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026