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Topical effect of tarragon oil extract on pain intensity, dryness and physical function of knee joint in patients with chronic osteoarthritis referred to Taleghani Gonbad Kavous Hospital in 1399

Topical effect of tarragon oil extract on pain intensity, dryness and physical function of knee joint in patients with chronic osteoarthritis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211203053264N1
Enrollment
90
Registered
2021-12-11
Start date
2021-12-18
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic osteoarthritis. Osteoarthritis of knee

Interventions

Intervention group: Patients were randomly divided into three intervention groups (topical application of 3% tarragon oil extract), sweet almond oil group, and control group. For this purpose, a lotte

Sponsors

Bojnourd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Confirmation of osteoarthritis of the knee by an orthopedic specialist Pain score = 4 at least in the last 3 months based on the VAS scale People who are able to understand the description and complete the interview Written and informed consent of the person Age 30-70 years No cancer, pregnancy and blood coagulation diseases such as hemophilia No wound above the knee joint No signs of acute infection at the knee joint No serious diseases such as liver disease and kidney failure No history of gastric ulcer disease, and skin lesions in the knee area No surgery to replace the knee joint or inject intra-articular steroids 90 days before the study. Do not suffer from abnormalities related to the lower limbs

Exclusion criteria

Exclusion criteria: 1- Taking oral and topical steroids for 14 days, alcoholism and drug addiction Patients with radiculopathy and neuropathy, patients with musculoskeletal diseases (including rheumatoid arthritis, septic arthritis, metabolic arthritis, gout and fibromyalgia) History of allergic reaction to sweet almond oil or tarragon-derived productsUse more than 2 grams per day of acetaminophen or other analgesics such as injectable drugs or other drugs such as glucosamine and chondroitin sulfate. Hospitalization Not wanting to continue participating in the study Travel and leave treatment

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: One week and three weeks after the intervention. Method of measurement: WOMAC questionnaire and VAS questionnaire.;Joint dryness. Timepoint: One week and three weeks after the intervention. Method of measurement: WOMAC Questionnaire.;Joint physical function. Timepoint: WOMAC Questionnaire. Method of measurement: One week and three weeks after the intervention.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoheila Abedpour

Birjand University of Medical Sciences

abedpur.0512@gmail.com+98 17 3322 6053

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026