Skip to content

Effect of Empagliflozin in prevention of kidney stone parameters

Evaluation of the Effect of Empagliflozin drug in prevention of urinal parameters increase in urolithiasis.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211203053261N2
Enrollment
138
Registered
2024-04-09
Start date
2023-01-21
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urolithiasis. Calculus of kidney with calculus of ureter

Interventions

Intervention 1: Intervention group: Patients will receive empagliflozin 10 mg daily for 4 weeks. Intervention 2: Control group: Patients will receive daily Starch tablets that look similar to Empaglif

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients in the age range of 18 to 65 years Patients with a history of kidney stones in the last 5 years

Exclusion criteria

Exclusion criteria: Diabetic patients Taking antidiabetic drugs Taking diuretic drugs Chronic kidney disease patients pregnancy Patients with genital infections Patients with urinary infections breastfeeding

Design outcomes

Primary

MeasureTime frame
24-hour urine calcium. Timepoint: Before the intervention and 4 weeks after the Start of Empagliflozin. Method of measurement: The ratio of urinary calcium to 24-hour urine volume.;24 hour Urine Oxalate. Timepoint: Before the intervention and 4 weeks after the Start of Empagliflozin. Method of measurement: The ratio of urinary Oxalate to 24-hour urine volume.;24 hour urine Uric acid. Timepoint: Before the intervention and 4 weeks after the Start of Empagliflozin. Method of measurement: The ratio of urinary Uric acid to 24-hour urine volume.;24 hour urine Phosphate. Timepoint: Before the intervention and 4 weeks after the Start of Empagliflozin. Method of measurement: The ratio of urinary Uric acid to 24-hour urine volume.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Mohammad Ataie

Hamedan University of Medical Sciences

mao_mohseni@yahoo.com+98 81 3838 0704

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026