Comparison of the skin effects of pretreatment preparation with chlorhexidine solution and povidone-iodine before rhinoplasty: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211121053135N1

Enrollment

Registered

2022-02-06

Start date

2021-12-22

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Urticaria. Condition 2: Erythema. Condition 3: Acne. Condition 4: Macula. Condition 5: Papula. Condition 6: Plaque. Condition 7: Seborrheic dermatitis. Condition 8: Perioral dermatitis. Condition 9: Allergic contact dermatitis. Condition 10: Itching. Condition 11: Burning. Condition 12: Scabbing. Urticaria Erythema infectiosum [fifth disease] Acne Macula Papula Plaque Seborrheic dermatitis Perioral dermatitis Allergic contact dermatitis Itching Burning Scabbing

Interventions

Intervention 1: Intervention group (first): in chlorhexidine group, face prepping before surgery is done by 2% chlorhexidine.one surgeon operate them with open method and with midazolam induction, nar

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ASA I or II health status. The patient is ready to take part in the study and sign the testimonial.

Exclusion criteria

Exclusion criteria: History of underlying diseases affecting the wound healing process like systemic diseases(diabetes, high blood pressure, gastrointestinal system diseases, kidney disorders, heart and lung diseases) Current consumption of drugs, alcohol, opiums (consumption of any of these substances during the last month) Pregnant women Any allergies or Hypersensitivities to the drugs used in this study

Design outcomes

Primary

Measure	Time frame
Initial outcome will be contain of erythema. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: Erythema will be studied on the basis of dermatologist opinion in this way: without, light, moderate and severe erythema.;Initial outcome will be contain of itching. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: Itching will be studied on the basis of ten parts scale Visual Analogue Scale with asking from patient.	—

Measure

Time frame

Initial outcome will be contain of erythema. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: Erythema will be studied on the basis of dermatologist opinion in this way: without, light, moderate and severe erythema.;Initial outcome will be contain of itching. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: Itching will be studied on the basis of ten parts scale Visual Analogue Scale with asking from patient.

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Secondary

Measure	Time frame
Secondary outcome is containing of burning. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: Burning will be studied on the basis of ten parts scale Visual Analogue Scale with asking from patient.;Secondary outcome is containing of acne. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of urticaria. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of macula. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of papula. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of allergic contact dermatitis. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of perioral dermatitis. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method o	—

Measure

Time frame

Secondary outcome is containing of burning. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: Burning will be studied on the basis of ten parts scale Visual Analogue Scale with asking from patient.;Secondary outcome is containing of acne. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of urticaria. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of macula. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of papula. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of allergic contact dermatitis. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method of measurement: They will be studied on the basis of dermatologist opinion in 4 group: without, slight, moderate and severe events.;Secondary outcome is containing of perioral dermatitis. Timepoint: Patients will be studied about skin effects 3 days later, one week later and one month later after surgery. Method o

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHoshyar Abbasi

Kermanshah University of Medical Sciences

hoshyar7ab@yahoo.com+98 83 3729 2254

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026