The effect of single oral dose vitamin D on left ventricular remodelling in patients with acute anterior left ventricular infarction referred to Shahid Rajaei Hospital and comparison with randomized clinical trial control group IRCT

The effect of single oral dose vitamin D on left ventricular remodelling in patients with acute anterior left ventricular infarction referred to Shahid Rajaei Hospital and comparison with randomized clinical trial control group IRCTcular

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211117053087N1

Enrollment

140

Registered

2022-02-19

Start date

2022-01-04

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with acute left ventricular anterior infarction who are candidates for angioplasty.

Interventions

Intervention 1: Intervention group: People in the intervention group are patients with acute anterior infarction of the left ventricle who are referred to Rajai Hospital in Karaj. If vitamin D is belo

Eligibility

Sex/Gender

All

Age

40 Years to 85 Years

Inclusion criteria

Inclusion criteria: age between 40_85 patients with Anterior infarction less than 12 hours after the onset of symptoms Patient informed consent to participate in the research project

Exclusion criteria

Exclusion criteria: history of infarction history of abnormal LVEF history of cardiomyopathy History of taking vitamin D supplements Moderate to severe valvular disease Calcium above 10.5 Allergy to vitamin D supplementation Individuals with BMI above 30 m2 / kg People who are not expected to stay in the study People with any life-threatening medical conditions renal failure liver failure People with a history of any known cancer Rheumatological and immunological diseases

Design outcomes

Primary

Measure	Time frame
LV EF. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVESDI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVESVI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVEDVI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVEDDI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;Diastolic function. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LV MASS. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;Sphercity Index. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;GLS. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;Troponin. Timepoint: At the beginning of the study and two months later. Method of measurement: Blood test.	—

Measure

Time frame

LV EF. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVESDI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVESVI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVEDVI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LVEDDI. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;Diastolic function. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;LV MASS. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;Sphercity Index. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;GLS. Timepoint: At the beginning of the study and two months later. Method of measurement: ECO TDI.;Troponin. Timepoint: At the beginning of the study and two months later. Method of measurement: Blood test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Basavand

Karaj University of Medical Sciences

ffatemehhbsv@gmail.com+98 919 772 3022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026