The effect of methylprednisolone pulse in patients with lumbar disc herniation

Comparison of the Effectiveness of Intravenous Infusion of Methylprednisolone 500 mg pulse with NSAIDs in lumbar disc herniation pain relief

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211116053077N1

Enrollment

Registered

2022-01-30

Start date

2022-02-01

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intervertebral disc disorders with radiculopathy, lumbar region. Intervertebral disc disorders with radiculopathy, lumbar region

Interventions

Intervention 1: Intervention group: Methylprednisolone Sodium Succinate 500 mg (Lyomedrol EXIR) pulse in 500 cc of Normal Saline intravenous infusion injection as a single dose in 1 hour for test grou

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Lumbar disc herniation visible in MRI Age above 18 History of low back pain radiating to lower limb in last 6 months Filling out informed consent form

Exclusion criteria

Exclusion criteria: Age under 18 Focal neurologic disorders existence History of vertebral surgery

Design outcomes

Primary

Measure	Time frame
Evaluation of pain relief in patients. Timepoint: The patient's condition is assessed one week after treatment, two weeks, three weeks, and one month and six months after treatment. Method of measurement: MRI.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Abiri

Ilam University of Medical Sciences

Mohammadabiri7@gmail.com+98 84 3222 7134

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 5, 2026