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The Effect of tranexamic acid on the volume of bleeding during and after elective cesarean section in moderate and high risk patients

The Effect of tranexamic acid on the volume of bleeding during and after elective cesarean section in moderate and high risk patients

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211114053061N1
Enrollment
200
Registered
2022-10-07
Start date
2021-05-07
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstetrics and Gynecology diseases. Encounter for care and examination of mother immediately after delivery

Interventions

Intervention 1: Intervention group: People are divided into one of the two groups receiving tranexamic acid (study group) or the group receiving 5% dextrose (control group). In all patients, cesarean

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Term pregnant mothers who are candidates for elective caesarean section have medium and high risk for postpartum bleeding Patients with history of postpartum hemorrhage in the past, presence of placenta previa, history of myomectomy, previous uterine surgery, multiple laparotomy, history of previous caesarean section more than 3 times, platelet count less than 75000, anemia with hemoglobin less than 10, polyhydramnios, macrosomia Weight more than 4000 grams, multiples, BMI more than 30, severe pregnancy complications such as preeclampsia

Exclusion criteria

Exclusion criteria: Unwillingness of patients to participate in the study and their infection with Corona Hypersensitivity to tranexamic acid VT Score more equal to 3 Underlying medical disease, placenta provia and placental adhesion disorders such as accreta and percreta, active bleeding and placental abruption, caesarean section with midline incision, drugs affecting tranexamic acid

Design outcomes

Primary

MeasureTime frame
Bleeding volume. Timepoint: During surgery and 6 hours after surgery. Method of measurement: Collecting the amount of gas and liquid and bottle suction.;Hematocrit level. Timepoint: During surgery and 6 hours after surgery. Method of measurement: laboratory.

Secondary

MeasureTime frame
Blood transfusion. Timepoint: After surgery. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTaraneh Arbabzadeh

Shahid Beheshti University of Medical Sciences

Tarbabzadeh@sbmu.ac.ir+98 21 2243 9770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026