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Efficacy and safety of rivaroxaban and subcutaneous enoxaparin after spinal surgery

Comparative efficacy and safety of rivaroxaban and subcutaneous enoxaparin in perevention of venous thrombo embolic events after spinal instrumentation

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211109053014N1
Enrollment
200
Registered
2021-12-19
Start date
2021-12-06
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intravenous thromboembolism. Thromboembolism in the puerperium

Interventions

Intervention 1: Intervention group: Administration of Rivarxaban 15 mg tablets once a day for 4 weeks after surgery from Dr. Obidi's factory. Intervention 2: Control group: Enoxaparin subcutaneous amp

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients undergoing spinal cord surgery Patient consent to participate in the study High risk of the patient for venous thromboembolism

Exclusion criteria

Exclusion criteria: Consumption of anticoagulants in the last 3 months Urine test with purpura-positive blood or cutaneous hematoma with active bleeding or high risk of bleeding Existence of active cancer as an underlying disease or cancer treated in the last 6 months Hospitalization and inactivity for more than 3 days Smoking more than 20 cigarettes a day Having a body mass index higher than 35 Pulmonary embolism and lower venous thrombosis

Design outcomes

Primary

MeasureTime frame
Intravenous Thromboembolism. Timepoint: In this study, hemorrhagic events caused by rivaroxaban and enoxaparin before surgery and 4 weeks after. Method of measurement: According to the patient's clinical symptoms.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Shafiei

Esfahan University of Medical Sciences

Mehdishafiei82@gmail.com+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026