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The effect of Platelet rich plasma on pregnancy in patients with repeated implantation failure .

Comparison of the effectiveness of one time and two times PRP and non-performing PRP in three groups of women with at least two or more pregnancy failures in high-quality embryo transfer who are candidates for embryo freezing in the embryo transfer cycle

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211108052998N1
Enrollment
180
Registered
2022-03-09
Start date
2022-03-25
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Does not apply. Because this study is not about diseases..

Interventions

Intervention 1: The first intervention group is the group in which PRP is infused only once for the patient. The initial preparation steps of the control and intervention groups are performed in the s

Sponsors

Fasa University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Satisfaction to enter the study Age <40 years Body mass index (BMI) <30 kg / m2

Exclusion criteria

Exclusion criteria: Existence of any uterine abnormalities (congenital or acquired) Existence of any uterine abnormalities (congenital or acquired) Uncontrolled hormonal disease ( prolactinemia or thyroid disease) and endometriosis Blood diseases (hemoglobin <9.0 g / dl and platelet count <100,000 per microliter) Chromosomal defects in the patient or spouse Lack of quality blastocysts (Grade A or B according to embryological score) for transmission

Design outcomes

Primary

MeasureTime frame
The study has only one outcome and the end result is a pregnancy test. At the end of the cycle, pregnancy is determined by laboratory evaluation of serum ß-HCG and the presence of fetal heartbeat on transvaginal ultrasound 2 weeks and 5 weeks after embryo transfer, respectively. Timepoint: evaluation of serum ß-HCG and the presence of fetal heartbeat on transvaginal ultrasound 2 weeks and 5 weeks after embryo transfer. Method of measurement: Transvaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Shahryari

Shiraz University of Medical Sciences

Zeinabsh3576@gmail.com+98 71 3233 2365

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026