Condition 1: Bronchopulmonary dysplasia. Condition 2: Respiratory Distress syndrome. Bronchopulmonary dysplasia originating in the perinatal period Respiratory distress syndrome of newborn
Conditions
Interventions
Intervention 1: Intervention group: Simultaneous intratracheal injection of surfactant (braksurf with an initial dose of 4 cc per kg body weight) and budesonide (budesonide at a dose of 0.25 mg / kg b
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 30 Days
Inclusion criteria
Inclusion criteria: Premature infants with a Gestational age less than 37 weeks weighing less than 1,500 g Premature infants admitted to the Neonatal ward due to Respiratory distress syndrome based on clinical and radiological symptoms and negative blood culture at birth; And receives any non-invasive respiratory support, and requires a surfactant injection at the physician's discretion.
Exclusion criteria
Exclusion criteria: Congenital major anomalies that affect the baby's breathing Existence of asphyxia; (Apgar score less than 7 in 5 minutes of birth) Parental dissatisfaction Gastrointestinal abnormalities that cause the baby to be transferred to another center Congenital cyanotic heart disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bronchopulmonary dysplasia. Timepoint: daily , end of 6 week or discharge time. Method of measurement: clinical.;Duration of auxiliary oxygen reception. Timepoint: daily , end of 6 week or discharge time. Method of measurement: clinical. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArezoo Aminyan daryasari
Iran University of Medical Sciences
Outcome results
None listed