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Effectiveness of hyaluronic acid in coronally advanced flap(CAF)

Effectiveness of hyaluronic acid application in coronally advanced flap(CAF) technique in root coverage

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211106052978N1
Enrollment
13
Registered
2021-12-02
Start date
2021-11-18
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingival recession. Gingival recession

Interventions

Intervention 1: For this research, the trapezoidal CAF technique based on Zucchelli method will be used. (60) After local anesthesia with a Persocaine-E 2% cartridge (lidocaine hydrochloride 20 mg, ep

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 years of age. Patients with O'LEARY Index (plaque control index) less than 20%. Presence of at least two buccal gingival analyzes (depth of analysis = 2mm) and no loss of interproximal joints (Miller class ??) in the anterior regions of the maxilla and mandible (central, lateral, canine, first and second premolars) that have bilateral Cosmetic problems or dental allergies. The presence of CEJ is clear and recognizable. Has sufficient gingival thickness. (thick biotype) Minimum keratinized gingival width (at least 1 mm for shallow lesions and 2 mm for = 5 mm lesions) Controls and cases patients in similar areas (type of jaw, type of tooth

Exclusion criteria

Exclusion criteria: Systemic disease pregnancy Active periodontal disease in the desired area. (Probe depth more than 4mm and BOP) Presence of veneer or restoration with edge on CEJ. History of periodontal surgery in the desired areas in the last 6 months. Smoking Long-term use of antibiotics in the last 6 months. Use of steroids and drugs affecting periodontal tissues

Design outcomes

Primary

MeasureTime frame
Probe depth. Timepoint: base line / 6 weeks later / 3 months later / 6 months later. Method of measurement: Probing Pocket Depth (PPD): Measured in the midfacial area from the gingival margin to the end of the pocket by a periodontal probe.;Recession depth. Timepoint: base line / 2 weeks later/ 6 weeks later / 3 months later / 6 months later. Method of measurement: Recession Depth (RD): In the midfacial area from the CEJ to the most apical margin of the gingival margin.;Recession width. Timepoint: base line / 2 weeks later/ 6 weeks later / 3 months later / 6 months later. Method of measurement: Recession Width (RW): The width of the gingival resorption is measured at the CEJ.;Width of keratinized tissue. Timepoint: base line / 2 weeks later/ 6 weeks later / 3 months later / 6 months later. Method of measurement: . The width of keratinized tissue, measured from the gingival margin to the MGJ, is measured in the medial region.;Mean root coverage. Timepoint: base line / 6 weeks later / 3 months later / 6 months later. Method of measurement: Mean Root Coverage (MRC): The average percentage of root surface previously It was exposed but is now covered. Based on this formula, it is calculated: (Depth of initial analysis ? RDi and depth of analysis day ? RDp () (RDi-RDp) / RDi × 100.;Complete root coverage. Timepoint: base line / 6 weeks later / 3 months later / 6 months later. Method of measurement: Complete Root Coverage (CRC): Percentage of patients whose root surface is completely covered. And is calculated based on this formula: (number of specimens that received full root cover ? NCRC and total number of specimens ? NT) NCRC / NT × 100.;Clinical attachment level. Timepoint: base line / 6 weeks later / 3 months later / 6 months later. Method of measurement: Clinical Attachment Level (CAL): In the midfacial areas of RD + PPD.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Saeed Sadatmansouri

Islamic Azad University

drsaeed_sadatmansouri@yahoo.com+98 21 5796 8828

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026