The efficacy of Vit A supplement in outcomes of medical treatment of ectopic pregnancy.

Evaluation of the efficacy of intramuscular Vitamin A supplementation compared to placebo in outcomes of medical treatment of ectopic pregnancy.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211103052950N4

Enrollment

100

Registered

2025-02-20

Start date

2025-03-05

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ectopic pregnancy. Ectopic pregnancy

Interventions

Intervention 1: Control group:Control group: or the group receiving methotrexate under the brand name Abitrex, a product of A B E W E, Austria, along with a placebo muscle injection vial, will be admi

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Aged between 18 and 40 years old. Confirmation of ectopic pregnancy based on hCG-ß titration and results of transvaginal ultrasound. There were no contraindications to prescribing methotrexate and vitamin A. Willingness to participate in a study

Exclusion criteria

Exclusion criteria: Liver and kidney function tests are abnormal Abnormal blood count Patients with advanced underlying disease

Design outcomes

Primary

Measure	Time frame
The number of times the methotrexate injection needs to be repeated. Timepoint: The fourth day, the seventh day, and the 11th day after the injection of methotrexate. Method of measurement: Determination of beta-hCG levels in serum before treatment using the ELISA technique.;Need for secondary treatment method (surgery). Timepoint: During hospitalisation. Method of measurement: Observations and Patient File.	—

Measure

Time frame

The number of times the methotrexate injection needs to be repeated. Timepoint: The fourth day, the seventh day, and the 11th day after the injection of methotrexate. Method of measurement: Determination of beta-hCG levels in serum before treatment using the ELISA technique.;Need for secondary treatment method (surgery). Timepoint: During hospitalisation. Method of measurement: Observations and Patient File.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Fateme Tabatabaei

Tabriz University of Medical Sciences

lahroudin@gmail.com0098 35539161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026