Pulmonary hypertension. Other secondary pulmonary hypertension
Conditions
Interventions
Intervention 1: Intervention group 1:The group that receiving Intravenous infusion of milrinone at a dose of 0.5 - 0.75 µg / kg / min. Medication regimens commence from the time of patient`s rewarming
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients who are candidate for heart valve transplantation and suffering pulmonary hypertension (right ventricular systolic pressure =50mmHg or meanPAP =40 mmHg or systolic PAP is mor than 50% of systemic systolic pressure) The age over 18 years old The consent of patient to being involved
Exclusion criteria
Exclusion criteria: Renal and hepatic failure Emergent surgery Necessity to inotropic drugs before surgery Long QT interval patients Drug allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary blood pressure in millimeters of mercury. Timepoint: After induction of anesthesia, before CPB, after CPB, the ICU arrival moment and every 6 hours till 24 hours in ICU. Method of measurement: Pulmonary artery catheter.;Ejection fraction. Timepoint: Before surgery and 3 days after surgery. Method of measurement: Echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMojtaba Mansouri
Esfahan University of Medical Sciences
Outcome results
None listed