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Comparison of the Effects of Metoclopramide and Lidocaine on Reducing Pain of Propofol with or without tourniquet

Comparison of the Effects of Metoclopramide and Lidocaine on Reducing Pain During Propofol IV Injection in general anesthesia induction with or without tourniquet , Kosar hospital , Semnan ,2021

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211101052932N1
Enrollment
120
Registered
2022-02-12
Start date
2021-11-22
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Each patient is a candidate for elective surgery who uses Propofol for anesthesia.(Comparison of the Effects of Metoclopramide and Lidocaine on Reducing Pain During Propofol IV Injection with or without tourniquet in general anesthesia induction ).

Interventions

Intervention 1: Group L1: injection of 2 mg / kg Propofol at a rate of 0.5 cc per second after injection of 40 mg Lidocaine. Intervention 2: Group L2: injection of 2 mg / kg Propofol at a rate of 0.5

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients must be in the American Society of Anesthesiology or ASA Class 1 and 2 . Have the ability to communicate verbally. All patients undergoing elective surgery who require general anesthesia, regardless of the type of surgery and the individual's disease.

Exclusion criteria

Exclusion criteria: People who are pregnant. Patients with a history of hypnotic, narcotic, or analgesic use in the 24 hours before the surgery or have a history of drug, analgesic, or alcohol dependence. Patients who are prohibited from taking Propofol (including allergies to foods such as eggs, soybeans, and Propofol), prohibition of lidocaine or metoclopramide, or other nonsteroidal anti-inflammatory drugs (NSAIDs). Patients with chronic pain syndromes, neurological or psychological diseases.

Design outcomes

Primary

MeasureTime frame
Pain score in VRS questionnaire. Timepoint: Immediately after intravenous injection of a quarter of Propofol in induction of anesthesia. Method of measurement: Pain intensity is assessed according to the Verbal Rating Scale(VRS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Abdollahpour

Semnan University of Medical Sciences

felordce@yahoo.com+98 23 3344 1022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026