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Comparison of the Effects of Ketorolac and Lidocaine on Reducing Pain of Propofol with or without tourniquet

Comparison of the Effects of Ketorolac and Lidocaine on Reducing Pain During Propofol IV Injection in general anesthesia induction with or without tourniquet

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211101052931N1
Enrollment
120
Registered
2021-12-02
Start date
2021-11-22
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Each patient is a candidate for elective surgery who uses Propofol for anesthesia.(Comparison of the Effects of Ketorolac and Lidocaine on Reducing Pain During Propofol IV Injection with or without tourniquet in general anesthesia induction ).

Interventions

Intervention 1: L1: Injection of 2 mg / kg Propofol at a rate of 0.5 cc per second after injection of 40 mg Lidocaine. Intervention 2: L2: Injection of 2 mg / kg Propofol at a rate of 0.5 cc per secon

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients must be in the American Society of Anesthesiology or ASA Class 1 and 2 . Have the ability to communicate verbally.

Exclusion criteria

Exclusion criteria: People who are pregnant. Patients with a history of hypnotic, narcotic, or analgesic use in the 24 hours before the surgery or have a history of drug, analgesic, or alcohol dependence Patients who are prohibited from taking Propofol (including allergies to foods such as eggs, soybeans, and Propofol), prohibition of lidocaine or ketorolac, or other nonsteroidal anti-inflammatory drugs (NSAIDs). Patients with chronic pain syndromes, neurological or psychological diseases. Patients who become allergic to drugs during the test.

Design outcomes

Primary

MeasureTime frame
Pain score in VRS questionnaire. Timepoint: Immediately after intravenous injection of a quarter of Propofol in induction of anesthesia. Method of measurement: Pain intensity is assessed according to the Verbal Rating Scale(VRS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Abdollahpoor

Semnan University of Medical Sciences

kosarhos@semums.ac.ir+98 23 3344 1022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026