The effect of acute exercise on cardiac autonomic nervous system (HR and HRV) of people with diabetes and presentation of regression model

Investigating the effect of acute exercise on cardiac autonomic nervous system indicators (HR and HRV) and correlation with the efficiency of the cardiopulmonary system in boys with type 1 diabetes at rest, during the GXT test, and during the exercise recovery period.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211031052926N2

Enrollment

Registered

2024-04-17

Start date

2024-04-20

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Boys with type 1 diabetes in Hamadan province. Type 1 diabetes mellitus

Interventions

Intervention 1: Intervention group: 1. HRV and resting HR (HRVrest and HRrest): The person is placed in a lying position on the medical bed, and then the average heart rate in the last 5 minutes of te

Eligibility

Sex/Gender

Male

Age

12 Years to 18 Years

Inclusion criteria

Inclusion criteria: Boys with type 1 diabetes Absence of disease and use of special medicine

Exclusion criteria

Exclusion criteria: Symptoms of diabetic neuropathy, cerebrovascular or eye diseases and respiratory failure Taking certain medications other than insulin Taking drugs that affect resting heart rate Have regular exercise during the week

Design outcomes

Primary

Measure	Time frame
HR: heart rate. Timepoint: Rest, during increased exercise and post-exercise recovery period. Method of measurement: R-R and HR intervals of each subject's electrocardiogram using a heart rate monitor (18630, Medset GmbH, Hamburg, Germany) with a sampling frequency of 1000 Hz from the ECG signal with an accuracy of 1 millisecond for each interval, for 5 minutes in a quiet and comfortable room between It was recorded from 9 to 12 in the morning in a supine position.After recording R-R intervals, HR and resting blood pressure measurements, HRVexe and HRexe, and cardiorespiratory capacity (VO2peak ml/kg/min) using Bruce modified incremental exercise test (GXT) and gas analyzer in the test room. Exercise was performed at the Farshchian Cardiology Hospital under the supervision of a cardiologist.;MR-R: Mean time between normal r waves. Timepoint: Rest, during increased exercise and post-exercise recovery period. Method of measurement: R-R and HR intervals of each subject's electrocardiogram using a heart rate monitor (18630, Medset GmbH, Hamburg, Germany) with a sampling frequency of 1000 Hz from the ECG signal with an accuracy of 1 millisecond for each interval, for 5 minutes in a quiet and comfortable room between It was recorded from 9 to 12 in the morning in a supine position.After recording R-R intervals, HR and resting blood pressure measurements, HRVexe and HRexe, and cardiorespiratory capacity (VO2peak ml/kg/min) using Bruce modified incremental exercise test (GXT) and gas analyzer in the test room. Exercise was performed at the Farshchian Cardiology Hospital under the supervision of a cardiologist.;SDNN: Standard Deviation of all Normal RR intervals. Timepoint: Rest, during increased exercise and post-exercise recovery period. Method of measurement: R-R and HR intervals of each subject's electrocardiogram using a heart rate monitor (18630, Medset GmbH, Hamburg, Germany) with a sampling frequency of 1000 Hz from the ECG signal with an accuracy of 1 millisecond fo	—

Measure

Time frame

HR: heart rate. Timepoint: Rest, during increased exercise and post-exercise recovery period. Method of measurement: R-R and HR intervals of each subject's electrocardiogram using a heart rate monitor (18630, Medset GmbH, Hamburg, Germany) with a sampling frequency of 1000 Hz from the ECG signal with an accuracy of 1 millisecond for each interval, for 5 minutes in a quiet and comfortable room between It was recorded from 9 to 12 in the morning in a supine position.After recording R-R intervals, HR and resting blood pressure measurements, HRVexe and HRexe, and cardiorespiratory capacity (VO2peak ml/kg/min) using Bruce modified incremental exercise test (GXT) and gas analyzer in the test room. Exercise was performed at the Farshchian Cardiology Hospital under the supervision of a cardiologist.;MR-R: Mean time between normal r waves. Timepoint: Rest, during increased exercise and post-exercise recovery period. Method of measurement: R-R and HR intervals of each subject's electrocardiogram using a heart rate monitor (18630, Medset GmbH, Hamburg, Germany) with a sampling frequency of 1000 Hz from the ECG signal with an accuracy of 1 millisecond for each interval, for 5 minutes in a quiet and comfortable room between It was recorded from 9 to 12 in the morning in a supine position.After recording R-R intervals, HR and resting blood pressure measurements, HRVexe and HRexe, and cardiorespiratory capacity (VO2peak ml/kg/min) using Bruce modified incremental exercise test (GXT) and gas analyzer in the test room. Exercise was performed at the Farshchian Cardiology Hospital under the supervision of a cardiologist.;SDNN: Standard Deviation of all Normal RR intervals. Timepoint: Rest, during increased exercise and post-exercise recovery period. Method of measurement: R-R and HR intervals of each subject's electrocardiogram using a heart rate monitor (18630, Medset GmbH, Hamburg, Germany) with a sampling frequency of 1000 Hz from the ECG signal with an accuracy of 1 millisecond fo

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz Fariba

Hamedan University of Medical Sciences

hossein.saki1990@yahoo.com+98 81 3827 3236

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026