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Evaluation of the effect of Unihemispheric Concurrent Dual-Site Transcranial Direct Current Stimulation of Dorsolateral Prefrontal Cortex AND primary motor cortex on improvement of lower limb motor function in patients with chronic stroke: A double-blind controlled clinical trial

Evaluation of the effect of Unihemispheric Concurrent Dual-Site Transcranial Direct Current Stimulation of Dorsolateral Prefrontal Cortex AND primary motor cortex on improvement of lower limb motor function in patients with chronic stroke: A double-blind controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211030052912N3
Enrollment
37
Registered
2023-01-28
Start date
2022-12-06
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke. Vascular syndromes of brain in cerebrovascular diseases

Interventions

Intervention 1: Intervention group: Anodal stimulation of the M1 and DLPFC of the involved side. The two-channel device 2-NEUROSTIM manufactured by Medina Medical Company will be used to create electr

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: First stroke Medial Cerebellar Artery (MCA) stroke The ability to verbally communicate with the therapist Patients using the Ashworth Modified Modified Scale (MMAS) to have a knee flexion muscle spasm severity of 1 or higher No history of a brain tumor Patients who do not have severe cognitive and memory disorders. To determine this, the Persian version of the Mini-Mental State Examination is used and patients must score at least 23 out of a total of 30

Exclusion criteria

Exclusion criteria: Patients with chronic neurological diseases such as Parkinson's, Alzheimer's, schizophrenia, radiculopathy, and musculoskeletal disorders, especially upper extremity movement disorders, diagnosed by a neurologist. History of seizures, previous brain surgery, heart disease and pacemaker Take drugs that change a person's cognitive status

Design outcomes

Primary

MeasureTime frame
Motor function. Timepoint: Before the first and after last electrical stimulation. Method of measurement: Fugl meyer test.;Brain metabolite activity,. Timepoint: Before the first and after last electrical stimulation. Method of measurement: Metabolite content with Magnetic resonance imaging.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomaye Azarnia

Rasht University of Medical Sciences

azarnia.pt.82@gmail.com+98 13 3334 6489

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026